Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
Stoelting™ Ugo Basile PAM Meter
Stoelting™ Pressure Application Measurement (PAM) device is an, easy-to-use tool for measuring mechanical pain threshold in experimental joint hypersensitivity models in rodents.
Supplier: Stoelting™ 58500PAW
Description
Designed and validated specifically for the mechanical stimulation and assessment of joint pain, ideal for detecting arthritis in rats and mice.
Operation
Specialized force sensor is worn on the thumb of the tester. Each PAM device comes standard with two force sensors, which have been specifically designed to apply force to rat and mouse joints and pedal switch. Computer software is also included for data acquisition.
Excellent for quantifying:
- Joint Sensitivity
- Chronic Joint Inflammation
- Arthritic Pain
Arthritis is associated with chronic, debilitating pain in the joints. Current metrics of arthritic pain are indirect, by scoring the level of motor activity or the animal's weight distribution. Current indirect tests, such as the weight distribution correlate well with the level of joint pain, but such a metric is a composite picture of complex pain responses, and provides little discrete information about local stimulation and locally-evoked responses.
The quantification of localized joint hypersensitivity is common in the clinic, but not in animal experiments. In this sense, the new PAM device represents a step forward toward a multifactorial measurement of pain-related behavior in animal research.
The PAM device is the first instrument designed specifically to apply force to the joint and automatically detect the animal's response.
Instrument Configuration
Pressure transducers: the PAM device comes with 2 different transducers. Each has been tested and validated in the mouse and rat knee joints: small transducer is flat and round (ideal for mouse knee joint), large transducer is flat and round (ideal for rat knee joint).
Specifications
| Neuroscience | |
| Mouse and Rat, Paw | |
| PAM meter |
Product Content Correction
Your input is important to us. Please complete this form to provide feedback related to the content on this product.
Product Title
Spot an opportunity for improvement?Share a Content Correction