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Invitrogen™ ULK2 Polyclonal Antibody
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Catalog No. PIPA534543
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100 μg
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Catalog No. Quantity
PIPA534543 100 μg
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Catalog No. PIPA534543 Supplier Invitrogen™ Supplier No. PA534543
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Description

Rabbit Polyclonal Antibody

A suggested positive control is human brain tissue lysate. PA5-34543 can be used with blocking peptide PEP-1586.

ULK2, also known as ATG1B, is a key serine/threonine protein kinase probably acting at the most upstream step of autophagosome formation. Knockout of ULK2 results in a severe defect in the autophagy pathway. ULK2 is highly conserved among eukaryotes and shows high homology with its related protein ULK1. Both ULK1 and ULK2 form a complex with ATG13 and FIP200 that mediates TOR signaling and is essential for autophagy. Like ULK1, ULK2 is also thought to be involved in early neuronal growth and differentiation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ULK2
Applications Immunohistochemistry, Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene ULK2
Gene Accession No. Q8IYT8
Gene Alias A830085I22Rik; ATG1B; AU015340; EC:2.7.11.1; KIAA0623; mKIAA0623; serine/threonine-protein kinase ULK2; Serine/threonine-protein kinase Unc51.2; ULK2; unc-51 like autophagy activating kinase 2; unc-51 like kinase 2; Unc51.2; unc-51-like kinase 2
Gene Symbols ULK2
Host Species Rabbit
Immunogen A 17 amino acid peptide near the center of human ULK2.
Purification Method Antigen Affinity Chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 9706
Target Species Human
Content And Storage Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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