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Apexbio Technology LLC Tipiracil hydrochloride 183204-72-0 10mM (in 1mL H2O)
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Supplier:  Apexbio Technology LLC A38755.1

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Tipiracil hydrochloride (CAS 183204-72-0) is a small-molecule inhibitor of thymidine phosphorylase (TP) an enzyme involved in the pyrimidine nucleoside salvage pathway By inhibiting TP tipiracil reduces the degradation of thymidine analogs thereby maintaining higher plasma concentrations of compounds such as trifluridine (FTD) when co-administered Tipiracil in combination with FTD constitutes the oral antitumor agent TAS-102 which is under clinical investigation In research settings tipiracil is used to enhance the pharmacological activity of nucleoside analogs by limiting their metabolic breakdown supporting studies on antitumor therapeutics and nucleotide metabolism

Catalog No. 50-000-96750


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