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UNC 0224, Tocris Bioscience™
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Catalog No. 386150
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Quantity:
10 mg
50 mg
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This item is not returnable. View return policy

Description

Potent G9a and GLP inhibitor

Potent G9a and GLP inhibitor (IC50 values are 15 and 20 nM in a ThioGlo assay, respectively). Exhibits >1000-fold selectivity for G9a over SET7, SET8 and SET9.

Chemical Identifiers

CAS 1197196-48-7
Molecular Formula C26H43N7O2
Molecular Weight (g/mol) 485.677
InChI Key XIVUGRBSBIXXJE-UHFFFAOYSA-N
Synonym 7-3-dimethylamino propoxy-6-methoxy-2-4-methyl-1,4-diazepan-1-yl-n-1-methylpiperidin-4-yl quinazolin-4-amine, n-debenzyl-n-methyl-o-demethyl-o-3-dimethylaminopropyl-bix 01294, 7-3-dimethylamino propoxy-2-hexahydro-4-methyl-1h-1,4-diazepin-1-yl-6-methoxy-n-1-methyl-4-piperidinyl-4-quinazolinamine
PubChem CID 44251522
IUPAC Name 7-[3-(dimethylamino)propoxy]-6-methoxy-2-(4-methyl-1,4-diazepan-1-yl)-N-(1-methylpiperidin-4-yl)quinazolin-4-amine
SMILES CN1CCCN(CC1)C2=NC3=CC(=C(C=C3C(=N2)NC4CCN(CC4)C)OC)OCCCN(C)C

Specifications

Quantity 50 mg
Formula Weight 485.67
Percent Purity >98%
Chemical Name or Material UNC 0224

Safety and Handling

Recommended Storage Store at +4°C
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