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Invitrogen™ UNC5D Polyclonal Antibody
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Catalog No. PIPA547137
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100 μg
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PIPA547137 100 μg
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Catalog No. PIPA547137 Supplier Invitrogen™ Supplier No. PA547137
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Description

Goat Polyclonal Antibody

Less than 5% cross-reactivity with recombinant rat (rr) UNC5H1, rrUNC5H2, and recombinant human UNC5H3 is observed. Reconstitute at 0.2 mg/mL in sterile PBS.

UNC5D, also named as KIAA1777 and UNC5H4, belongs to the unc-5 family. It is a receptor for netrin. It may be involved in axon guidance by mediating axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding. Axon repulsion in growth cones may be caused by its association with DCC that may trigger signaling for repulsion. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand.
TRUSTED_SUSTAINABILITY

Specifications

Antigen UNC5D
Applications Western Blot
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 5% trehalose and No Preservative
Gene UNC5D
Gene Accession No. Q6UXZ4
Gene Alias D930029E11Rik; FLJ16019; KIAA1777; KIAA1777Unc5h4; mKIAA1777; Netrin receptor UNC5D; netrin receptor Unc5h4; PRO34692; Protein unc-5 homolog 4; protein unc-5 homolog D; unc5 homolog 4; unc-5 homolog 4; unc-5 homolog D; unc-5 homolog D (C. elegans); unc-5 netrin receptor D; UNC5D; UNC5H4; UNQ6012/PRO34692
Gene Symbols UNC5D
Host Species Goat
Immunogen Mouse myeloma cell line NS0-derived recombinant human UNC5H4 Gly15-Ser373.
Purification Method Antigen Affinity Chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 137970
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Lyophilized
Isotype IgG
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