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Tocris Bioscience™ UPF 648

Catalog No. 492610
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492610 10 mg
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Catalog No. 492610 Supplier Tocris Bioscience™ Supplier No. 4926/10
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Description

Potent kynurenine 3-monooxygenase (KMO) inhibitor

UPF 648 is a potent kynurenine 3-monooxygenase (kynurenine 3-hydroxylase; KMO) inhibitor (IC50 = 20 nM). Increases kynurenic acid levels, and decreases 3-HK and QUIN levels in cerebrum and liver of neonatal rodents. Neuroprotective in a Drosophila model of Huntington's disease.

Specifications

Chemical Name or Material (1S,2S)-2-(3,4-Dichlorobenzoyl)cyclopropanecarboxylic acid
CAS 213400-34-1
Quantity 10 mg
Target Hydroxylase Inhibitors
Molecular Formula C11H8Cl2O3
Formula Weight 259.09
Purity >98%
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