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Tocris Bioscience™ UPF 648

Potent kynurenine 3-monooxygenase (KMO) inhibitor

Manufacturer:  Tocris Bioscience™ 4926/10

Catalog No. 492610


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Description

Description

Potent kynurenine 3-monooxygenase (kynurenine 3-hydroxylase; KMO) inhibitor (IC50 = 20 nM). Increases kynurenic acid levels, and decreases 3-HK and QUIN levels in cerebrum and liver of neonatal rodents. Neuroprotective in a Drosophila model of Huntington's disease.
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