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MilliporeSigma™ Upstate In Vivo Shape Reagent (Live Cell RNA Structure Analysis)

Ready to use RNase-free solution with low toxicity to use with live cells for determination of RNA structure

Supplier:  MilliporeSigma™ 03310

Catalog No. 03-310-MI


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Description

Description

  • High cell-permeability for rapid modification of RNA
  • Reacts with all RNA nucleotides for high resolution mapping
  • Contains highly pure form of 2-methylnicotinic acid imidazolide (NAI)
  • Forms 2'-O-adducts on single stranded regions of RNA that can be detected by Selective 2'-Hydroxyl Acylation Primer Extension (SHAPE)
  • NAI rapidly absorbed into cells, formulated to have low levels of toxicity for use with live cells
  • Reacts in unbiased fashion with all four RNA nucleotides
  • Combination of low toxicity, rapid uptake lack of nucleotide bias enables high resolution RNA structure analysis in variety of living systems
  • Packaging: Vial
  • Color: Clear, Colourless

Recommended Storage

Store NAI at −20°C in a non-frost-ree freezer protected from light

TRUSTED_SUSTAINABILITY
Specifications

Specifications

2-methylnicotinic acid imidazolide (NAI) in DMSO In Vivo Shape Reagent
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