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Diagnostic Biosystems UROPLAKIN III AU1 Uroplakin III

Supplier:  Diagnostic Biosystems MOB594

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Uroplakins (UPs) are a family of transmembrane proteins (UPs Ia, Ib, II and III) that are specific differentiation products of urothelial cells. In nonneoplastic mammalian urothelium, UPs are expressed in the luminal surface plasmalemma of superficial (umbrella) cells, forming complexes of 16nm crystalline particles. UPIII isspecific for tumors of urothelial origin and, when used in combination with other markers, can aid in the diagnosis of primary and metastatic tumors.

Catalog No. 50-238-5369


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