Invitrogen™ USP6 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5104204

Catalog No. PIPA5104204

Description

Antibody detects endogenous levels of total USP6.

USP6 is a deubiquitinase with an ATP-independent isopeptidase activity, cleaving at the C-terminus of the ubiquitin moiety. It catalyzes its own deubiquitination. In vitro, isoform2, but not isoform3, shows deubiquitinating activity. USP6 promotes plasma membrane localization of ARF6 and selectively regulates ARF6-dependent endocytic protein trafficking. It is able to initiate tumorigenesis by inducing the production of matrix metalloproteinases following NF-kappa-B activation.

Specifications

• Antigen: USP6
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: USP6
• Gene Alias: Deubiquitinating enzyme 6; HRP1; hyperpolymorphic gene 1; proto-oncogene TRE-2; TBC1D3 and USP32 fusion; TRE17; TRE2; Tre-2; TRESMCR; Ubiquitin carboxyl-terminal hydrolase 6; ubiquitin specific peptidase 6; ubiquitin specific peptidase 6 (Tre-2 oncogene); ubiquitin specific protease 6 (Tre-2 oncogene); ubiquitin thioesterase 6; ubiquitin thiolesterase 6; ubiquitin-specific protease USP6; ubiquitin-specific-processing protease 6; USP6; USP6-short
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 9098
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P35125
• Gene Symbols: USP6
• Immunogen: A synthesized peptide derived from human USP6(Accession P35125), corresponding to amino acid residues Y1366-Q1406.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov