Invitrogen™ Uteroglobin Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5102469

Catalog No. PIPA5102469

Description

Antibody detects endogenous levels of total SCGB1A1.

Uteroglobin, which is a member of the Secretoglobin superfamily and is also known as Clara cell phospholipid-binding protein, is a multifunctional protein that can exert anti-inflammatory and anti-tumorigenic effects by binding small hydrophobic molecules such as phospholipids and prostaglandins. The small, non-glycosylated protein named for its high levels of expression in pre-implantation embryos, where it exhibits growth stimulatory effects, is produced and secreted by the non-ciliated, non-mucous Clara cells predominant in the epithelial surfaces of pulmonary airways, as well as other non-ciliated epithelia. Members of the Secretoglobin superfamily demonstrate a high level of structural conservation and are characterized as small, secretory homo- or heterodimers. In addition to sequestering pro-inflammatory mediators and carcinogens, Uteroglobin has been implicated in the inhibition of cell migration and invasion, platelet aggregation, and T cell differentiation.

Specifications

• Antigen: Uteroglobin
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SCGB1A1
• Gene Alias: Blastokinin; CC10; CC16; CCPBP; CCSP; Clara cell 17 kDa protein; clara cell phospholipid-binding protein; clara cell secretory protein; clara cells 10 kDa secretory protein; PCBB; PCB-binding protein; PCB-BP; SCGB1A1; Secretoglobin family 1A member 1; secretoglobin, family 1A, member 1 (uteroglobin); UG; Ugb; UP1; UP-1; Urinary protein 1; urine protein 1; uteroglobin; Uteroglobin (Clara cell secretory protein); Utg
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 22287, 25575, 7356
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P11684, P17559, Q06318
• Gene Symbols: SCGB1A1
• Immunogen: A synthesized peptide derived from human SCGB1A1(Accession P11684), corresponding to amino acid residues A45-N91.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG