Vδ2 TCR Mouse anti-Human, BUV395, Clone: B6, BD Optibuild™

Catalog No.	Quantity
BDB743754	50 μg

Catalog No. BDB743754 Supplier BD Biosciences Supplier No. 743754

Description

Mouse Monoclonal Antibody

The B6 monoclonal antibody specifically recognizes the human variableδ2 subunit (Vδ2) of theγ/δT cell receptor (TCR). Theγ/δTCR is composed of two disulfide linked glycoproteins. The delta chain is approximately 40-60 kDa and is restricted to peripheral blood T cells and thymocytes. The majority of normal peripheral bloodγ/δT cells express a Vγ9[+]/ Vδ2[+] phenotype. The reason for this selection in the T-cell repertoire is not well understood.

The antibody was conjugated to BD Horizon™ BUV395 which is part of the BD Horizon Brilliant™ Ultraviolet family of dyes. This dye has been exclusively developed by BD Biosciences to have minimal spillover into other detectors, making it an optimal choice for multicolor flow cytometry. With an Ex Max at 348 nm and an Em Max at 395 nm, BD Horizon BUV395 can be excited with a 355 nm laser and detected with a 379/28 filter. BUV395 is a UV-excitable dye that has been developed exclusively by BD Biosciences. With an excitation max of 348 nm and emission max of 395 nm, BUV395 can be excited by the 355nm laser and detected in a 379/28 filter. This dye is optimal for multicolor flow cytometry because it has little to no spillover into other detectors.

Specifications

• Antigen: Vδ2 TCR
• Classification: Monoclonal
• Clone: B6
• Concentration: 0.2mg/mL
• Conjugate: Brilliant Ultraviolet 395
• Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
• Gene Alias: TCR Vδ2
• Host Species: Mouse
• Immunogen: Human TCR Vδ2 Recombinant Protein
• Purification Method: Affinity Purified
• Quantity: 50 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Target Species: Human
• Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
• Isotype: IgG1 κ