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Tocris Bioscience™ Vandetanib

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Quantity:
10 mg
50 mg
Description
Vandetanib is a potent VEGFR-2 inhibitor (IC50 = 0.04 μM), and inhibitor of EGFR (IC50 = 0.5 μM). Vandetanib potently inhibits (IC50 = 100 nM) RET oncoprotein activity in human thyroid cancer. Vandetanib displays anti-angiogenic properties in human nasopharyngeal carcinoma in mice model. Vandetanib is orally available and effective in vivo.
Specifications
Specifications
Chemical Name or Material | N-(4-Bromo-2-fluorophenyl)-6-methoxy-7-[(1-methyl-4-piperidinyl)methoxy]-4-quinazolinamine |
CAS | 443913-73-3 |
Quantity | 50 mg |
Target | VEGF Receptor Inhibitors |
Molecular Formula | C22H24BrFN4O2 |
Purity | 0.98 |
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