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Invitrogen™ VE-cadherin Monoclonal Antibody (55-7H1), Alexa Fluor™ 647
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Catalog No. PIMA544146
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100 Tests
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PIMA544146 100 Tests
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Catalog No. PIMA544146 Supplier Invitrogen™ Supplier No. MA544146
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Mouse Monoclonal Antibody

This antibody recognizes a calcium-independent extracellular epitope on CD144 (VE-cadherin, cadherin 5), an adhesion molecule expressed on endothelial cells.

VE-cadherin is a member of the cadherin superfamily that is located in a six-cadherin cluster in a region on the long arm of chromosome 16 and is involved in loss of heterozygosity events in breast and prostate cancer. VE-cadherin protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classic cadherin by imparting to cells the ability to adhere in a homophilic manner, VE-cadherin may play an important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. An alternative splice variant has been described but the full length sequence of VE-cadherin has not been determined.
TRUSTED_SUSTAINABILITY

Specifications

Antigen VE-cadherin
Applications Flow Cytometry, Western Blot, Immunocytochemistry
Classification Monoclonal
Clone 55-7H1
Concentration 0.160 mg/mL
Conjugate Alexa Fluor 647
Formulation PBS with 0.2% BSA and 15mM sodium azide
Gene CDH5
Gene Accession No. P33151
Gene Alias 7B4; 7B4 antigen; 7B4/cadherin-5; AA408225; cadherin 5; cadherin 5, type 2 (vascular endothelium); cadherin 5, type 2, VE-cadherin (vascular endothelium); cadherin 5, type 2, VE-cadherin (vascular epithelium); cadherin-5; cadherin-5; cd144 antigen; VE cadherin; Cd144; cd144 antigen; CDH5; cell-cell adhesion protein; endothelial-specific cadherin; vascular endothelial cadherin; vascular endothelial cadherin precursor; Vec; VEcad; VE-Cad; VE-cadherin; VECD
Gene Symbols CDH5
Host Species Mouse
Immunogen Human endothelial cells.
Purification Method Size-exclusion chromatography
Quantity 100 Tests
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1003
Target Species Human
Content And Storage 4°C, store in dark, DO NOT FREEZE!
Product Type Antibody
Form Liquid
Isotype IgG1 κ
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WARNING: Cancer - www.P65Warnings.ca.gov
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