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Invitrogen™ VEGF Receptor 2 Monoclonal Antibody (KDR-2 or 260.4)
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Catalog No. PIMA124888
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50 μL
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PIMA124888 50 μL
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Catalog No. PIMA124888 Supplier Invitrogen™ Supplier No. MA124888
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Description

Mouse Monoclonal Antibody

The predicted molecular weight is 152 kDa. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

KDR (FLK1, VEGFR2) is a type III receptor tyrosine kinase. It binds vascular endothelial growth factor with high affinity in vitro, and is expressed early in development by endothelial cell precursors. FLK1 (VEGF Receptor 2) encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc. Mutations of FLK1 (VEGF Receptor 2) are implicated in infantile capillary hemangiomas.
TRUSTED_SUSTAINABILITY

Specifications

Antigen VEGF Receptor 2
Applications ELISA, Immunohistochemistry (Frozen), Western Blot
Classification Monoclonal
Clone KDR-2 or 260.4
Concentration 4.3 mg/mL
Conjugate Unconjugated
Formulation Ascites with 15mM sodium azide
Gene KDR
Gene Accession No. P35968
Gene Alias 6130401C07; CD309; CD309 antigen; fetal liver kinase 1; fetal liver kinase-1; FLK1; Flk-1; FLK1 kinase insert domain receptor (a type III receptor tyrosine kinase) (VEGF receptor 2); FLK1 kinase insert domain receptor (VEGF receptor 2); flk-1 type VEGF receptor; KDR; kinase insert domain protein receptor; kinase insert domain receptor; kinase insert domain receptor (a type III receptor tyrosine kinase); kinase NYK; Krd-1; Ly73; protein-tyrosine kinase receptor flk-1; sCD309; soluble CD309; soluble vascular endothelial growth factor receptor 2; soluble VEGFR 2; soluble VEGFR2; sVEGFR-2; tyrosine kinase growth factor receptor; vascular endotheial growth factor 2; vascular endothelial growth factor receptor 2; vascular endothelial growth factor receptor- 2; vascular endothelial growth factor receptor-2; vascular endothelial growth factor receptor-3; VEGF R2; VEGF receptor-2; VEGFR; VEGFR2; VEGFR-2
Gene Symbols KDR
Host Species Mouse
Immunogen Purified recombinant human extracellular VEGF receptor-2 (KDR).
Quantity 50 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3791
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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