Invitrogen™ VGAT Monoclonal Antibody (CL2793)

Catalog No.	Quantity
PIMA524643	100 μL

Catalog No. PIMA524643 Supplier Invitrogen™ Supplier No. MA524643

Description

Mouse Monoclonal Antibody

Immunogen sequence: ATSVSNKSQA KMSGMFARMG FQAATDEEAV GFAHCDDLDF EHRQGLQMDI LKAEGEPCGD EGAEAPVEGD IHYQRGSGAP LPPSGSKDQV G Highest antigen sequence identity to the following orthologs: Mouse - 95%, Rat - 93%.

The Vesicular GABA Amino Acid Transporter (VGAT) is responsible for transport of the inhibitory neurotransmitter into synaptic vesicles (McIntire et al., 1997). The VGAT protein (also known as the Vesicular Inhibitory Amino Aid Transporter or VIAAT) is expressed in synaptic vesicles of both glycine and GABAergic synapses throughout the CNS (Chaudhry et al., 1998). Expression of the VGAT protein changes during development and also in response to patterns of neuronal activity (De et al., 2005).

Specifications

• Antigen: VGAT
• Applications: Immunohistochemistry (Paraffin)
• Classification: Monoclonal
• Clone: CL2793
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene: SLC32A1
• Gene Accession No.: O35458, O35633, Q9H598
• Gene Alias: GABA and glycine transporter; GVAT; hVIAAT; mVGAT; mVIAAT; R75019; rGVAT; SLC32A1; solute carrier family 32 (GABA vesicular transporter), member 1; solute carrier family 32 member 1; vasicular inhibitory amino acid transporter 10D; vesicular GABA transporter; Vesicular inhibitory amino acid transporter; Vgat; Viaat
• Gene Symbols: SLC32A1
• Host Species: Mouse
• Immunogen: Recombinant protein fragment of Human SLC32A1 (Product #RP-99348)
• Purification Method: Protein A
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 140679, 22348, 83612
• Target Species: Human, Mouse, Rat
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1