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VNN1 Rabbit anti-Human, Mouse, Polyclonal, Proteintech
SDP

Catalog No. 501733575 Shop All Proteintech Group Inc Products
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50-173-3575 150 μL
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Catalog No. 50-173-3575 Supplier Proteintech Group Inc Supplier No. 217451AP150UL
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Description

Rabbit Polyclonal Antibody

Hematopoietic precursor cells migrate to the thymus, where they differentiate into mature T lymphocytes. GPI-anchored vanin-1 protein regulates the late adhesion steps of thymus homing of bone marrow precursor cells. Vanin-1 is ubiquitously expressed as a pantetheinase enzyme and catalyzes the hydrolysis of pantetheine for vitamin B5 recycling. The hydrolytic activity of vanin-1 generates the potent antioxidant cysteamine as a metabolite. As a membrane bound pantetheinase, vanin-1 provides the main source of cysteamine under normal physiological conditions. In mice, vanin-1 is expressed specifically in male Sertoli cells of the developing testis, where it aids in cell migration.

Specifications

Antigen VNN1
Applications Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 0.37 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene VNN1
Gene Accession No. O95497, Q9Z0K8
Gene Alias HDLCQ8, Pantetheinase, Pantetheine hydrolase, Tiff66, vanin 1, VNN1
Gene Symbols VNN1
Host Species Rabbit
Immunogen VNN1 Fusion Protein Ag16501
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 22361, 8876
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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