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Apexbio Technology LLC Odanacatib (MK-0822) 603139-19-1 5mg
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Supplier:  Apexbio Technology LLC A24875

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Odanacatib (MK-0822 CAS 603139-19-1) is a potent orally bioavailable and selective inhibitor of cathepsin K exhibiting an IC50 of 0 2 nM Cathepsin K is predominantly expressed in osteoclasts where it plays an essential role in the degradation of bone collagen matrix and bone resorption By inhibiting cathepsin K odanacatib suppresses bone resorption while partially preserving bone formation as demonstrated in both preclinical studies and phase IIb clinical trials in postmenopausal women Odanacatib is under investigation for its potential to reduce fracture risk in osteoporosis research

Catalog No. 50-000-94810


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