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Invitrogen™ VPARP Monoclonal Antibody (P193-10)
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Catalog No. 01672051
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01-672-051 1 mL
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Catalog No. 01-672-051 Supplier Invitrogen™ Supplier No. MA135745
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Description

Mouse Monoclonal Antibody

p193-10 reacts with an internal epitope (amino acids 506-510, VALGK) of the minor vault protein (p193 or VPARP), which is overexpressed in various human non-P-glycoprotein MDR tumor cell lines, accordingly to an increase in the number of vault particles. p193-10 was raised against an E. coli lysate transformed with the pET28a(+) expression vector containing amino acids 408-611 of the p193 cDNA.

This gene encodes poly(ADP-ribosyl)transferase-like 1 protein, which is capable of catalyzing a poly(ADP-ribosyl)ation reaction. This protein has a catalytic domain which is homologous to that of poly (ADP-ribosyl) transferase, but lacks an N-terminal DNA binding domain which activates the C-terminal catalytic domain of poly (ADP-ribosyl) transferase. Since this protein is not capable of binding DNA directly, its transferase activity may be activated by other factors such as protein-protein interaction mediated by the extensive carboxyl terminus.
TRUSTED_SUSTAINABILITY

Specifications

Antigen VPARP
Applications Flow Cytometry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone P193-10
Concentration 0.25 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA and 0.1% sodium azide
Gene PARP4
Gene Accession No. Q9UKK3
Gene Alias 193 kDa vault protein; ADP-ribosyltransferase (NAD+; ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase)-like 1; ADP-ribosyltransferase diphtheria toxin-like 4; ADPRTL1; ARTD4; C030027K23Rik; E230037B21Rik; Gm743; H5 proline-rich; I-alpha-I-related; KIAA0177; p193; Parp4; PARP-4; PARPL; PARP-related; PARP-related/IalphaI-related H5/proline-rich; PH5P; poly (ADP-ribose) polymerase family, member 4; poly (ADP-ribose) polymerase)-like 1; poly [ADP-ribose] polymerase 4; poly(ADP-ribose) polymerase family member 4; poly(ADP-ribose) synthetase; poly(ADP-ribosyl)transferase-like 1; Protein mono-ADP-ribosyltransferase PARP4; Vault poly(ADP-ribose) polymerase; vault protein, 193-kDa; VAULT3; von Willebrand factor A domain containing 5C; VPARP; VWA5C
Gene Symbols PARP4
Host Species Mouse
Immunogen VPARP aa 408-611.
Purification Method purified
Quantity 1 mL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 143
Target Species Human
Content And Storage 4°C
Product Type Antibody
Form Liquid
Isotype IgG2b κ
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