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Invitrogen™ VPS51 Polyclonal Antibody
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Catalog No. PIPA521674
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100 μL
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PIPA521674 100 μL
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Catalog No. PIPA521674 Supplier Invitrogen™ Supplier No. PA521674
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: A431, HeLa, HepG2. Predicted reactivity: Mouse (99%), Zebrafish (88%), Xenopus laevis (83%), Chicken (80%), Bovine (99%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Acts as component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN). The GARP complex is required for the maintenance of protein retrieval from endosomes to the TGN, acid hydrolase sorting, lysosome function, endosomal cholesterol traffic and autophagy. VPS51 participates in retrograde transport of acid hydrolase receptors, likely by promoting tethering and SNARE-dependent fusion of endosome-derived carriers to the TGN. Acts as component of the EARP complex that is involved in endocytic recycling. The EARP complex associates with Rab4-positive endosomes and promotes recycling of internalized transferrin receptor (TFRC) to the plasma membrane.
TRUSTED_SUSTAINABILITY

Specifications

Antigen VPS51
Applications Western Blot
Classification Polyclonal
Concentration 0.26 mg/mL
Conjugate Unconjugated
Formulation 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Gene VPS51
Gene Accession No. Q9UID3
Gene Alias 1110014N23Rik; 3110057M17Rik; AI837850; ANG2; ANG3; Another new gene 2 protein; C11orf2; C11orf3; Ffr; PP5382; Protein fat-free homolog; vacuolar protein sorting 51 homolog; vacuolar protein sorting 51 homolog (S. cerevisiae); vacuolar protein sorting-associated protein 51 homolog; VPS51; VPS51 GARP complex subunit; VPS51, GARP complex subunit
Gene Symbols VPS51
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the C-terminus region of human C11orf2. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 738
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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