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VRK1 Rabbit anti-Human, Polyclonal, Bethyl Laboratories

Catalog No. 501569976
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50-156-9976 10 μL
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Catalog No. 50-156-9976 Supplier Bethyl Laboratories, Inc Supplier No. A305268AT
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Description

Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt.

This gene encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. This gene is widely expressed in human tissues and has increased expression in actively dividing cells, such as those in testis, thymus, fetal liver, and carcinomas. Its protein localizes to the nucleus and has been shown to promote the stability and nuclear accumulation of a transcriptionally active p53 molecule and, in vitro, to phosphorylate Thr18 of p53 and reduce p53 ubiquitination. This gene, therefore, may regulate cell proliferation. This protein also phosphorylates histone, casein, and the transcription factors ATF2 (activating transcription factor 2) and c-JUN.

Specifications

Antigen VRK1
Applications Immunoprecipitation
Classification Polyclonal
Concentration 1 mg/ml
Conjugate Unconjugated
Formulation phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene VRK1
Gene Accession No. Q99986
Gene Alias Vaccinia related kinase 1, MGC117401, MGC138280, Serine/threonine-protein kinase VRK1, Vaccinia-related kinase 1
Gene Symbols VRK1
Host Species Rabbit
Immunogen Between 1 and 50
Purification Method Antigen affinity chromatography
Quantity 10 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 7443
Target Species Human
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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