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VU 0240551, Tocris Bioscience™

Catalog No. 388850
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Catalog No. Quantity
38-885-0 50 mg
38-881-0 10 mg
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Catalog No. 38-885-0 Supplier R&D Systems Supplier No. 3888/50
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Description

KCC2 inhibitor

Inhibitor of the neuronal K-Cl cotransporter, KCC2 (IC50 = 560 nM for K+ uptake assay in KCC2-overexpressing cells). Exhibits selectivity over the Na-K-2Cl cotransporter, NKCCl. Also inhibits hERG and L-type Ca2+ channels.

Chemical Identifiers

CAS 893990-34-6
Molecular Formula C16H14N4OS2
Molecular Weight (g/mol) 342.435
InChI Key WJRWSLORVIHRNX-UHFFFAOYSA-N
Synonym n-4-methyl-2-thiazolyl-2-6-phenyl-3-pyridazinyl thio-acetamide, n-4-methyl-2-thiazolyl-2-6-phenyl-3-pyridazinyl thio acetamide, n-4-methyl-1,3-thiazol-2-yl-2-6-phenylpyridazin-3-yl thio acetamide, n-4-methylthiazol-2-yl-2-6-phenylpyridazin-3-ylthio acetamide, n-4-methyl-1,3-thiazol-2-yl-2-6-phenylpyridazin-3-yl sulfanylacetamide, n-4-methyl-1,3-thiazol-2-yl-2-6-phenylpyridazin-3-yl sulfanyl acetamide, d0m2pp, cid, vu hplc, n-4-methylthiazol-2-yl-2-6-phenylpyridazin-3-yl thio acetamide
PubChem CID 7211972
IUPAC Name N-(4-methyl-1,3-thiazol-2-yl)-2-(6-phenylpyridazin-3-yl)sulfanylacetamide
SMILES CC1=CSC(=N1)NC(=O)CSC2=NN=C(C=C2)C3=CC=CC=C3

Specifications

Quantity 50 mg
Formula Weight 342.43
Percent Purity >99%
Chemical Name or Material VU 0240551

Safety and Handling

Recommended Storage Store at +4°C
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