Tocris Bioscience™ VU 0463271 

Potent and selective KCC2 inhibitor

Manufacturer:  Tocris Bioscience™ 4719/10

Catalog No. 47-191-0

Description

Potent and selective inhibitor of the neuronal K-Cl cotransporter, KCC2 (IC50 = 61 nM); displays >100-fold selectivity versus the Na-K-2Cl cotransporter 1 (NKCC1) and no activity against a panel of 68 GPCRs, ion channels and transporters.

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Specifications

• Chemical Name or Material: N-Cyclopropyl-N-(4-methyl-2-thiazolyl)-2-[(6-phenyl-3-pyridazinyl)thio]acetamide
• CAS: 1391737-01-1
• Formula Weight: 382.5
• Product Type: Target: Other Ion Pump/Transporter Inhibitors

• Purity: >98%
• Molecular Formula: C₁₉H₁₈N₄OS₂
• Quantity: 10mg

Safety and Handling

Recommended Storage : Store at 4°C