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Apexbio Technology LLC ω-Agatoxin IVA(Synonyms: Omega-Agatoxin IVA, ω-Aga IVA, Omega-Aga IVA, Agatoxin IVA, ω-Agatoxin-IVA, Aga IVA, ω-Aga-IVA), 10ug, CAS: 145017-83-0.

Supplier: Apexbio Technology LLC B71920.01

ω-Agatoxin IVA (CAS 145017-83-0) is a peptide neurotoxin isolated originally from spider venom. It selectively inhibits voltage-gated P/Q-type calcium channels (Cav2.1), blocking calcium ion influx across neuronal membranes. By binding with high affinity to these calcium channels, ω-Agatoxin IVA suppresses neurotransmitter release at presynaptic terminals. Researchers routinely utilize ω-Agatoxin IVA to investigate neurotransmission, presynaptic calcium signaling, and the physiological or pathological roles of P/Q-type calcium channels in neuronal function.
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