WDFY3 Rabbit anti-Human, Polyclonal, Bethyl Laboratories
Rabbit Polyclonal Antibody
Supplier: Bethyl Laboratories, Inc A301869A
The recommended shelf life for this product is 1 year from date of receipt. Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.Required for selective autophagy (aggrephagy) but not for autophagic degradation of bulk cytospol in response to starvation. Involved in the formation and degradation of cytoplasmic polyubiquitin-containing bodies (p62 bodies, ALIS/aggresome-like induced structures). May play a role as adaptor or scaffolding protein by promoting the association of the E3-like ligase ATG12-ATG5-ATG16L and LC3 to ubiquitinated target substrate. The association with GABARAP is required for its recruitment to LC3B-positive p62 bodies suggesting a role in targeting certain p62 structures for clearance. Involved in midbody ring degradation.
|ALFY, autophagy-linked FYVE protein, KIAA0993, ZFYVE25|
|Antigen affinity chromatography|
|Immunohistochemistry, Immunoprecipitation, Western Blot|
|phosphate, tris citrate with 0.09% sodium azide; pH 7-8|
|Between 500 and 550|
The Fisher Scientific Encompass Program offers items which are not part of our distribution portfolio. These products typically do not have pictures or detailed descriptions. However, we are committed to improving your shopping experience. Please use the form below to provide feedback related to the content on this product.
Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.Ok