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WDR24 Rabbit anti-Human, Mouse, Polyclonal, Proteintech
SDP

Catalog No. 501733078 Shop All Proteintech Group Inc Products
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50-173-3078 150 μL
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Catalog No. 50-173-3078 Supplier Proteintech Group Inc Supplier No. 207781AP150UL
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Description

Rabbit Polyclonal Antibody

WDR24, as a component of the GATOR subcomplex GATOR2, functions within the amino acid-sensing branch of the TORC1 signaling pathway. Indirectly activates mTORC1 and the TORC1 signaling pathway through the inhibition of the GATOR1 subcomplex. WDR24 is negatively regulated by the upstream amino acid sensors SESN2 and CASTOR1. In addition to its role in regulation of the TORC1 complex, promotes the acidification of lysosomes and facilitates autophagic flux.

Specifications

Antigen WDR24
Applications Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 0.25 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene WDR24
Gene Accession No. Q8CFJ9, Q96S15
Gene Alias C16orf21, JFP7, WD repeat domain 24, WDR24
Gene Symbols Wdr24
Host Species Rabbit
Immunogen WDR24 Fusion Protein Ag14774
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 268933, 84219
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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