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Description
Recommended positive controls: Jurkat, Raji, NCI-H929, Neuro2A, C8D30, C2C12. Predicted reactivity: Mouse (95%), Rat (96%), Xenopus laevis (84%), Chicken (88%), Bovine (98%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
WEE1, which is classified as a Ser/Thr kinase by sequence analysis, has been shown to inactivate multiple CDKs by tyrosine phosphorylation. Wee1 protein catalyzes the inhibitory tyrosine phosphorylation of CDC2/cyclin B kinase, and appears to coordinate the transition between DNA replication and mitosis by protecting the nucleus from cytoplasmically activated CDC2 kinase.
Specifications
Specifications
| Antigen | WEE1 |
| Applications | Immunohistochemistry (Paraffin), Western Blot |
| Classification | Polyclonal |
| Concentration | 1.45 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 20% glycerol and 0.025% ProClin 300; pH 7 |
| Gene | WEE1 |
| Gene Accession No. | P30291, P47810 |
| Gene Alias | CTRCT30; DKFZp686I18166; epididymis luminal protein 113; fa20h03; FLJ16446; HEL113; VIM; Vimentin; wee 1 homolog; WEE 1 homolog 1 (S. pombe); Wee1; WEE1 G2 checkpoint kinase; WEE1 homolog; wee1 protein; WEE1 tyrosine kinase; WEE1+ homolog; Wee1A; wee1A kinase; WEE1hu; wee1-like protein kinase; wu:fa20h03; zgc:136514 |
| Gene Symbols | WEE1 |
| Show More |
Product Title
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