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WEE2 Rabbit anti-Human, Polyclonal, Proteintech
SDP

Catalog No. 501735997 Shop All Proteintech Group Inc Products
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50-173-5997 150 μL
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Catalog No. 50-173-5997 Supplier Proteintech Group Inc Supplier No. 551191AP150UL
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Description

Rabbit Polyclonal Antibody

The antibody is specific to WEE2.

Oocyte-specific protein tyrosine kinase that phosphorylates and inhibits CDK1 and acts as a key regulator of meiosis during both prophase I and metaphase II. Required to maintain meiotic arrest in oocytes during the germinal vesicle (GV) stage, a long period of quiescence at dictyate prophase I, by phosphorylating CDK1 at ′Tyr-15′, leading to inhibit CDK1 activity and prevent meiotic reentry. Also required for metaphase II exit during egg activation by phosphorylating CDK1 at ′Tyr-15′, to ensure exit from meiosis in oocytes and promote pronuclear formation.

Specifications

Antigen WEE2
Applications Western Blot
Classification Polyclonal
Concentration 0.47 mg/mL
Conjugate Unconjugated
Formulation 0.1 M glycine, 0.1 M sodium bicarbonate with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene WEE2
Gene Accession No. P0C1S8
Gene Alias WEE1 homolog 2 (S. pombe), Wee1 like protein kinase 1B, Wee1 like protein kinase 2, WEE1B, Wee1B kinase, WEE2
Gene Symbols WEE2
Host Species Rabbit
Immunogen Peptide
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 494551
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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