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WIPI2 Polyclonal Antibody, Bethyl Laboratories

Catalog No. 501570135
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50-157-0135 20 μL
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Catalog No. 50-157-0135 Supplier Bethyl Laboratories, Inc Supplier No. A305324AT
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Description

Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt. Based on 100% sequence identity, this antibody is predicted to react with Rat and Chicken

WD repeat proteins play a role in many essential biologic functions, regulating the assembly of multiprotein complexes by presenting a beta-propeller platform for simultaneous and reversible protein-protein interactions. WIPI2, also known as ATG18B or ATG21, is a human homolog to yeast ATG18 and contains three WD repeats and has a 7-bladed propeller structure with a conserved motif that facilitates its interaction with other proteins. It is recruited to early autophagosomal structures along with Atg16L and ULK1 and is required for the formation of LC3-positive autophagosomes. Along with the highly related WIPI1, WIPI2 is found at the plasma membrane in addition to autophagosomal membranes.

Specifications

Antigen WIPI2
Applications Western Blot
Classification Polyclonal
Conjugate Unconjugated
Formulation TBS with 0.1% BSA and 0.09% sodium azide
Gene WIPI2
Gene Accession No. Q80W47, Q9Y4P8
Gene Alias ATG18B, Atg21, WIPI-2, WD repeat domain phosphoinositide-interacting protein 2, WD40 repeat protein interacting with phosphoinositides 2, WIPI49-like protein 2
Gene Symbols WIPI2
Host Species Rabbit
Immunogen Between 404 and 454
Purification Method Antigen affinity chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 26100, 74781
Target Species Human, Mouse
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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