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  5. Tocris Bioscience™ WWL 123

Tocris Bioscience™ WWL 123
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Catalog No. 531750
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

α/β-hydrolase domain 6 (ABHD6) inhibitor; antiepileptic

WWL 123 is an α/β-hydrolase domain 6 (ABHD6) inhibitor (IC50 = 0.43 μM). Blocks PTZ -induced seizures in healthy mice and spontaneous seizures in R6/2 mice. Antiepileptic activity is independent of CB1 and CB2 receptors, but is GABAA receptor dependent. Brain penetrant.

Specifications

Chemical Name or Material N-[[1,1′-Biphenyl]-3-ylmethyl)-N-methylcarbamic acid 4′-(aminocarbonyl)[1,1′-biphenyl]-4-yl ester
CAS 1338574-83-6
Quantity 50 mg
Target Hydrolase Inhibitors
Molecular Formula C28H24N2O3
Formula Weight 436.5
Purity >98%
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