Invitrogen™ XK Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA590227

Catalog No. PIPA590227

Description

Immunogen sequence: HRDLSRDRPL VLLLHLLQLG PLFRCFEVFC IYFQSGNNEE PYVSITKKRQ MPKNGLSEEI EKEVGQAEGK LITHRSAFSR; Positive Samples: mouse pancreas, rat pancreas; Cellular Location: Membrane, Multi-pass membrane protein.

The XK protein is a membrane-bound protein associated with the endoplasmic reticulum (ER) and forms part of the ER membrane complex (EMC), which is critical for various cellular processes. This protein is involved in the insertion, folding, and assembly of membrane proteins in eukaryotic cells. The XK protein's role in the ER highlights its importance in maintaining proper cell function, as the ER is integral in protein synthesis, lipid metabolism, and calcium storage. Furthermore, the XK protein's involvement in these processes underscores its significance in cellular homeostasis and its potential contribution to pathologies when mutated or dysfunctional.

Specifications

• Antigen: XK
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: XK
• Gene Alias: 1810038K19Rik; Kell blood group precursor (McLeod phenotype); Kell blood group precursor (McLeod phenotype) homolog; kell complex 37 kDa component; KX; Kx antigen; MCLDS; McLeod syndrome gene homolog; membrane transport protein XK; NA; NAC; neuroacanthocytosis; neurocanthocytosis; X1k; Xk; XK homolog; XK, Kell blood group complex subunit (McLeod syndrome); Xkh; XKR1; XK-related protein 1; X-linked Kx blood group; X-linked Kx blood group (McLeod syndrome); X-linked Kx blood group (McLeod syndrome) homolog; Xrg1
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 22439, 497078, 7504
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot, Immunocytochemistry
• Concentration: 2.00 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: P51811, Q5GH61, Q9QXY7
• Gene Symbols: XK
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 59-138 of human XK (NP_0665691).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov