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XPF Mouse anti-Canine, Human, Mouse, Rat, Clone: UMAB20, lyophilized, UltraMAB™
SDP

Catalog No. 501684876
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100 μg
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Catalog No. Quantity
50-168-4876 100 μg
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Catalog No. 50-168-4876 Supplier OriGene Supplier No. UM500020CF
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Description

Mouse Monoclonal Antibody

The structure specific ERCC 1 / XPF endonuclease complex is implicated in the repair of two distinct types of lesions in DNA: NER for UV induced lesions and bulky chemical adducts; and recombination repair of the very genotoxic interstrand cross links. NER mechanism involves dual incisions on both sides of the damage catalyzed by two nucleases. In mammalian cells, XPG cleaves 3′ of the DNA lesion while the ERCC1 / XPF complex makes the 5′ incision. ERCC1 / XPF probably plays a role in processing partially processed recombination intermediates.

Specifications

Antigen XPF
Applications Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Peptide Array
Classification Monoclonal
Clone UMAB20
Conjugate Unconjugated
Formulation PBS with 8% trehalose and no preservative
Gene ERCC4
Gene Accession No. Q92889, Q9QZD4
Gene Alias ERCC11, FANCQ, RAD1, XFEPS, XPF
Gene Symbols Ercc4
Host Species Mouse
Immunogen Full length human recombit protein of human XPF produced in HEK293 cell.
Purification Method Affinity Chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2072, 304719, 479842, 50505
Target Species Canine, Human, Mouse, Rat
Content And Storage -20° C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Lyophilized
Isotype IgG2a
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