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Invitrogen™ XRCC1 Polyclonal Antibody
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Catalog No. PIPA582259
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PIPA582259 100 μL
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Catalog No. PIPA582259 Supplier Invitrogen™ Supplier No. PA582259
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: WDRVKIVCSQ PYSKDSPFGL SFVRFHSPPD KDEAEAPSQK VTVTKLGQFR VKEEDESANS LRPGALFFSR INKTSPVTAS DPAGPSYAAA TLQASSAASS ASPVSRAIGS TSKPQESPKG KRKLDLNQEE KKT Highest antigen sequence indentity to the following orthologs: Mouse - 85%, Rat - 85%.

XRCC1 (X-ray cross complementing factor-1) is involved in DNA base excision repair. XRCC1 is a 70 kDa protein that has been shown to be physically associated with other DNA repair enzymes, including poly (ADP-ribose) polymerase (PARP), DNA Ligase III and DNA polymerase beta. XRCC1 contains a BRCT domain (for BRCA1 carboxyl terminus) which was originally found in the tumor suppressor protein BRCA1. Recently, the BRCT domain has been shown to mediate the protein-protein interaction of XRCC1 and DNA ligase III-alpha.
TRUSTED_SUSTAINABILITY

Specifications

Antigen XRCC1
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.20 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene XRCC1
Gene Accession No. P18887
Gene Alias DNA repair protein XRCC1; RCC; X-ray repair complementing defective repair in Chinese hamster cells 1; X-ray repair cross complementing 1; x-ray repair cross-complementing group 1 protein; X-ray repair cross-complementing protein 1; XRCC1; Xrcc-1
Gene Symbols XRCC1
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human XRCC1. Recombinant protein control fragment (Product #RP-89468).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 7515
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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