XRCC4 Mouse anti-Human, Clone: 3E5D2, Proteintech

Catalog No.	Quantity
50-173-7039	150 μL

Catalog No. 50-173-7039 Supplier Proteintech Group Inc Supplier No. 666211IG150UL

Description

Mouse Monoclonal Antibody

The x-ray repair cross-complementing (XRCC) proteins are responsible for efficiently repairing and maintaining genetic stability following DNA base damage. These genes share sequence similarity with the yeast DNA repair protein Rad51. XRCC4 is an accessory factor of DNA ligase IV that preferentially binds DNA with nicks or broken ends. XRCC4 binds to DNA ligase IV and enhances its joining activity, and it is also involved in V(D)J recombination. Any defect in one of the known components of the DNA repair/V(D)J recombination machinery (Ku-70, Ku-80, DNA-PKCS, XRCC4 and DNA ligase IV) leads to abortion of the V(D)J rearrangement process and early block in both T and B cell maturation.

Specifications

• Antigen: XRCC4
• Applications: Immunohistochemistry (Paraffin), Western Blot
• Classification: Monoclonal
• Clone: 3E5D2
• Concentration: 0.83 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene: XRCC4
• Gene Accession No.: Q13426
• Gene Alias: DNA repair protein XRCC4, XRCC4
• Gene Symbols: XRCC4
• Host Species: Mouse
• Immunogen: XRCC4 Fusion Protein Ag8807
• Purification Method: Protein A
• Quantity: 150 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 7518
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG2b