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Lkt Laboratories CAS 129830-38-2, ≥99%, ROCK inhibitor that prevents binding of Ras-related GTPase Rho A, altering actin cytoskeleton reorganization, cell adhesion, and cell migration.
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Supplier:  Lkt Laboratories Y1000

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Y27632 is a selective inhibitor of Rho-associated protein kinase (ROCK); Y27632 binds to the catalytic site of ROCK, preventing binding of Ras-related GTPase Rho A, which is involved in actin cytoskeleton reorganization, cell adhesion, and cell migration. Y27632 inhibits downstream endothelin and TGF-β-related signaling. This compound exhibits neuroprotective and neuromodulatory activity, displaying benefit in animal models of Parkinson’s Disease and inhibiting conditioned place aversion in animal models of memory formation. Reduces dissociation-induced apoptosis in embryonic and neural stem cells. Increases stem cell cloning efficiency.

Catalog No. NC2539832


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