Thermo Scientific Chemicals Yohimbine hydrochloride, 98+%

Catalog No.	Quantity
AAJ6018503	1 g

Catalog No. AAJ6018503 Supplier Thermo Scientific Chemicals Supplier No. J6018503

Description

CAS: 65-19-0 | C21H27ClN2O3, C₂₁H₂₆N₂O₃·HCl | 390.91 g/mol

Yohimbine hydrochloride is an α2-adrenergic receptor antagonist. It blocks the central α2-adrenegic receptors in the brain, thus preventing and reducing the effects of xylazine, an α2-adrenergic agonist. The sedative effects and respiratory depression that accompany xylazine administration are both antagonized and reversed by yohimbine. Yohimbine hydrochloride also produces an antidiuretic effect, and increases heart rate and blood pressure.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Specifications

Chemical Identifiers

• CAS: 65-19-0
• Molecular Formula: C₂₁H₂₆N₂O₃·HCl, C21H27ClN2O3
• Molecular Weight (g/mol): 390.91
• InChI Key: PIPZGJSEDRMUAW-VJDCAHTMSA-N
• Synonym: 17-Hydroxyyohimban-16-carboxylic acid methyl ester hydrochloride
• IUPAC Name: hydrogen methyl (1S,15R,18S,19R,20S)-18-hydroxy-3,13-diazapentacyclo[11.8.0.0²,¹⁰.0⁴,⁹.0¹⁵,²⁰]henicosa-2(10),4,6,8-tetraene-19-carboxylate chloride
• SMILES: [H+].[Cl-].COC(=O)[C@H]1[C@@H](O)CC[C@H]2CN3CCC4=C(NC5=CC=CC=C45)[C@@H]3C[C@H]12

• Quantity: 1 g
• Description: White to Off-white
• For Use With (Application): Standard alpha-2-adrenergic antagonist
• Formula Weight: 390.91g/mol
• Sensitivity: Light Sensitive
• Melting Point: 288°C to 290°C
• Product Type: Signal Transduction Reagent
• Form: Powder
• Assay: ≥98%

Safety and Handling

EINECSNumber	200-600-4
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only