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Invitrogen™ ZC3H13 Polyclonal Antibody
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Catalog No. PIPA5101961
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PIPA5101961 100 μL
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Catalog No. PIPA5101961 Supplier Invitrogen™ Supplier No. PA5101961
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total ZC3H13.

The zinc finger CCCH domain-containing protein 13 (ZC3H13) is a 1668 amino acid protein that contains one C3H1-type zinc finger. ZC3H13 is phosphorylated upon DNA damage, most likely by ATM or ATR. Two isoforms of ZC3H13 exists as a result of alternative splicing events. The gene encoding ZC3H13 maps to chromosome 13, which contains around 114 million base pairs and 400 genes. Key tumor suppressor genes on chromosome 13 include the breast cancer susceptibility gene, BRCA2, and the RB1 (retinoblastoma) gene. As with most chromosomes, polysomy of part or all of chromosome 13 is deleterious to development and decreases the odds of survival. Trisomy 13, also known as Patau syndrome, is quite deadly and the few who survive past one year suffer from permanent neurologic defects, difficulty eating and vulnerability to serious respiratory infections.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ZC3H13
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene ZC3H13
Gene Accession No. E9Q784, Q5T200
Gene Alias 2600010B19Rik; 3110050K21Rik; 4930570G11Rik; C87618; KIAA0853; RGD1307729; ZC3H13; Zinc finger CCCH domain-containing protein 13; zinc finger CCCH type containing 13; zinc finger CCCH-type containing 13
Gene Symbols ZC3H13
Host Species Rabbit
Immunogen A synthesized peptide derived from human ZC3H13(Accession Q5T200), corresponding to amino acid residues R1577-N1627.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 23091, 67302
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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