Invitrogen™ ZC3HAV1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA531650

Catalog No. PIPA531650

Description

Recommended positive controls: 293T, A431, HeLa, HepG2. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The zinc finger antiviral protein (ZC3HAV1) is a CCCH type zinc finger protein that induces an innate immunity to infections by retrovirus by preventing the accumulation of viral RNAs in the cytoplasm and recruits the RNA processing exosome to degrade target RNAs, thereby inhibiting virus replication. ZC3HAV1 is localized in the cytoplasm at steady state, but shuttles between nucleus and cytoplasm in a XPO1-dependent manner. ZAP is a direct target gene of IRF3 action in cellular antiviral responses.

Specifications

• Antigen: ZC3HAV1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Zc3hav1
• Gene Alias: 1200014N16Rik; 2900058M19Rik; 9130009D18Rik; 9830115L13Rik; ADP-ribosyltransferase diphtheria toxin-like 13; ARTD13; CCCH-type zinc finger antiviral protein (Zap); D6Bwg1452e; FLB6421; Inactive Poly [ADP-ribose] polymerase 13; PARP13; PRO1677; rZAP; ZAP; ZC3H2; Zc3hav1; ZC3HDC2; zinc finger antiviral protein; Zinc finger CCCH domain-containing protein 2; zinc finger CCCH type, antiviral 1; zinc finger CCCH-type antiviral protein 1; zinc finger CCCH-type containing, antiviral 1; zinc finger CCCH-type, antiviral 1
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 56829
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1.35 mg/mL
• Formulation: PBS with 20% glycerol and 0.025% ProClin 300; pH 7
• Gene Accession No.: Q7Z2W4
• Gene Symbols: Zc3hav1
• Immunogen: Recombinant fragment corresponding to a region within amino acids 401 and 721 of Human ZC3HAV1.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG