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ZC3HAV1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
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Catalog No. 501731199 Shop All Proteintech Group Inc Products
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50-173-1199 150 μL
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Catalog No. 50-173-1199 Supplier Proteintech Group Inc Supplier No. 168201AP150UL
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Rabbit Polyclonal Antibody

The zinc finger antiviral protein (ZC3HAV1) is a CCCH type zinc finger protein that induces an innate immunity to infections by retrovirus by preventing the accumulation of viral RNAs in the cytoplasm and recruits the RNA processing exosome to degrade target RNAs, thereby inhibiting virus replication. ZC3HAV1 is localized in the cytoplasm at steady state, but shuttles between nucleus and cytoplasm in a XPO1-dependent manner. ZAP is a direct target gene of IRF3 action in cellular antiviral responses.

Specifications

Antigen ZC3HAV1
Applications Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 0.37 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene ZC3HAV1
Gene Accession No. Q3UPF5, Q7Z2W4, Q8K3Y6
Gene Alias FLB6421, ZAP, ZC3H2, ZC3HAV1, ZC3HDC2, Zinc finger antiviral protein
Gene Symbols ZC3HAV1
Host Species Rabbit
Immunogen ZC3HAV1 Fusion Protein Ag10364
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 252832, 56829, 78781
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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