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Invitrogen™ ZFYVE19 Polyclonal Antibody
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Catalog No. PIPA565320
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100 μL
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PIPA565320 100 μL
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Catalog No. PIPA565320 Supplier Invitrogen™ Supplier No. PA565320
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: SGCLSFSAAVP RTGNTQQKVC KQCHEVLTRG SSANASKWSP PQNYKKRVAA LEAKQKPSTS QSQGLTRQDQ MIAERLARLR QENKPKLVPS Q Highest antigen sequence identity to the following orthologs - mouse 85%, rat 85%.

Key regulator of abscission step in cytokinesis: part of the cytokinesis checkpoint, a process required to delay abscission to prevent both premature resolution of intercellular chromosome bridges and accumulation of DNA damage. Together with CHMP4C, required to retain abscission-competent VPS4 (VPS4A and/or VPS4B) at the midbody ring until abscission checkpoint signaling is terminated at late cytokinesis. Deactivation of AURKB results in dephosphorylation of CHMP4C followed by its dissociation from ZFYVE19/ANCHR and VPS4 and subsequent abscission.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ZFYVE19
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.9 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene ZFYVE19
Gene Accession No. Q96K21
Gene Alias 1500041L05Rik; abscission/NoCut checkpoint regulator; ANCHR; MLL partner containing FYVE domain; MPFYVE; Zfyve19; Zinc finger FYVE domain-containing protein 19; zinc finger FYVE-type containing 19; zinc finger, FYVE domain containing 19
Gene Symbols ZFYVE19
Host Species Rabbit
Immunogen Recombinant Human ZFYVE19. Recombinant protein control fragment (Product #RP-104747).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 84936
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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