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  6. ZFYVE21 Rabbit anti-Human, Polyclonal, Proteintech 

ZFYVE21 Rabbit anti-Human, Polyclonal, Proteintech
SDP

Catalog No. 501734555 Shop All Proteintech Group Inc Products
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50-173-4555 150 μL
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Catalog No. 50-173-4555 Supplier Proteintech Group Inc Supplier No. 248061AP150UL
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Description

Rabbit Polyclonal Antibody

ZF21 was initially identified as protein that could bind to the cytoplasmic tail of MT1-MMP (Membrane-type 1 matrix metalloproteinase), a potent invasion-promoting protease. ZF21 is a member of a protein family characterized by the presence of a phosphatidylinositol 3-phosphate-binding FYVE domain and regulates focal adhesions (FAs) and cell movement. Knockdown of ZF21 expression resulted in a delay of FA disassembly following induction of synchronous disassembly of FAs by nocodazole treatment, suggesting that ZF21 is involved in FA disassembly. ZF21 contains a noncanonical pleckstrin homology domain that is a possible therapeutic target to treat metastatic cancer.

Specifications

Antigen ZFYVE21
Applications Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 0.4 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene ZFYVE21
Gene Accession No. Q9BQ24
Gene Alias ZFYVE21
Gene Symbols ZFYVE21
Host Species Rabbit
Immunogen ZFYVE21 Fusion Protein Ag20024
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 79038
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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