Invitrogen™ ZFYVE9 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA597180

Catalog No. PIPA597180

Description

Immunogen sequence: MENYFQAEAY NLDKVLDEFE QNEDETVSST LLDTKWNKIL DPPSHRLSFN PTLASVNESA VSNESQPQLK VFSLAHSAPL TTEEEDHCAN GQDCNLNPEI ATMWIDENAV AEDQLIKRNY SWDDQCSAVE VGEKKCGNLA CLPDEKNVLV VAVMHNCDKR TLQNDLQDCN NYNSQSLMDA FSCSLDNENR QTDQFSFSIN ESTEKDMNSE KQMDPLNRPK TEGRSVNHLC PTSSDSLASV CSPSQLKDDG SIGRDPSMSA; Positive Samples: LO2, HeLa; Cellular Location: Cytoplasm, Early endosome membrane.

Early endosomal protein that functions to recruit SMAD2/SMAD3 to intracellular membranes and to the TGF-beta receptor. Plays a significant role in TGF-mediated signaling by regulating the subcellular location of SMAD2 and SMAD3 and modulating the transcriptional activity of the SMAD3/SMAD4 complex. Possibly associated with TGF-beta receptor internalization.

Specifications

• Antigen: ZFYVE9
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Zfyve9
• Gene Alias: E030027L17; hSARA; MAD, mothers against decapentaplegic homolog interacting protein, receptor activation anchor; MADH-interacting protein; MADHIP; Mothers against decapentaplegic homolog-interacting protein; Novel serine protease; NSP; PPP1R173; protein phosphatase 1, regulatory subunit 173; Receptor activation anchor; SARA; Smad anchor for receptor activation; SMADIP; ZFYVE9; Zinc finger FYVE domain-containing protein 9; zinc finger FYVE-type containing 9; zinc finger, FYVE domain containing 9
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 9372
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 0.9 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: O95405
• Gene Symbols: Zfyve9
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human ZFYVE9 (NP_0047902).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov