ZGPAT Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Supplier:  Proteintech Group Inc 232031AP150UL

Catalog No. 50-173-4019

Description

Transcription repressor that specifically binds the 5′-GGAG[GA]A[GA]A-3′ consensus sequence. Represses transcription by recruiting the chromatin multiprotein complex NuRD to target promoters. Negatively regulates expression of EGFR, a gene involved in cell proliferation, survival and migration. Its ability to repress genes of the EGFR pathway suggest it may act as a tumor suppressor. Able to suppress breast carcinogenesis. Isoform 4: Antagonizes the transcription repression by isoform 1 by competing for the binding of the NuRD complex. Does not bind DNA.

Specifications

• Antigen: ZGPAT
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ZGPAT
• Gene Alias: GPATC6, GPATCH6, KIAA1847, ZC3H9, ZC3HDC9, ZGPAT, ZIP
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 229007, 84619
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.24 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q8N5A5, Q8VDM1
• Gene Symbols: ZGPAT
• Immunogen: ZGPAT Fusion Protein Ag19620
• Quantity: 150 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG