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ZGPAT Rabbit anti-Human, Mouse, Polyclonal, Proteintech
SDP

Catalog No. 501734019 Shop All Proteintech Group Inc Products
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50-173-4019 150 μL
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Catalog No. 50-173-4019 Supplier Proteintech Group Inc Supplier No. 232031AP150UL
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Description

Rabbit Polyclonal Antibody

Transcription repressor that specifically binds the 5′-GGAG[GA]A[GA]A-3′ consensus sequence. Represses transcription by recruiting the chromatin multiprotein complex NuRD to target promoters. Negatively regulates expression of EGFR, a gene involved in cell proliferation, survival and migration. Its ability to repress genes of the EGFR pathway suggest it may act as a tumor suppressor. Able to suppress breast carcinogenesis. Isoform 4: Antagonizes the transcription repression by isoform 1 by competing for the binding of the NuRD complex. Does not bind DNA.

Specifications

Antigen ZGPAT
Applications Western Blot
Classification Polyclonal
Concentration 0.24 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene ZGPAT
Gene Accession No. Q8N5A5, Q8VDM1
Gene Alias GPATC6, GPATCH6, KIAA1847, ZC3H9, ZC3HDC9, ZGPAT, ZIP
Gene Symbols ZGPAT
Host Species Rabbit
Immunogen ZGPAT Fusion Protein Ag19620
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 229007, 84619
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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