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Invitrogen™ Zika Virus Envelope (strain Zika SPH2015) Recombinant Rabbit Monoclonal Antibody (033), HRP
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Catalog No. MA560379
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MA560379 100 μg
MA560380 20 μg
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Catalog No. MA560379 Supplier Invitrogen™ Supplier No. MA560379
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Description

Rabbit Recombinant Monoclonal Antibody

Zika Virus Envelope (strain Zika SPH2015) Recombinant Monoclonal Antibody for ELISA

As a member of the Flaviviridae family, ZIKV has a single positive sense RNA genome, which is initially translated as a single polyprotein which is then cleaved post-transitionally into three structural proteins (C, PrM or M, and E) and seven nonstructural (NS) proteins (NS1, NS2A, NS2B, NS3, NS4A, NS4B and NS5)(1). The glycosated NS1 forms a homodimer inside the cells and is necessary for viral replication and late in infection (2). NS1 is also secreted into the extracellular space as a hexameric lipoprotein particle, which assists the virus in immune evasion and pathogenesis by interacting with components from both innate and adaptive immune systems as well as other host factors (1). Reference 1) Song, H.; Qi, J.; Haywood, J.; Shi, Y.; Gao, G.F. (2016). Nat. Struct. Mol. Biol. 23, 456-458. 2) Suthar, M.S., Diamond, M.S. and Gale, M. Jr. (2013). Nat. Rev. Microbiol. 11, 115-128.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Zika Virus Envelope (strain Zika SPH2015)
Applications ELISA
Classification Recombinant Monoclonal
Clone 033
Concentration 1 mg/mL
Conjugate HRP
Formulation PBS with no preservative
Gene Alias Zika Envelope
Host Species Rabbit
Immunogen Recombinant Zika virus (ZIKV) (strain Zika SPH2015) ZIKV-E/Envelope protein (Domain III) protein (Val593-Lys699).
Purification Method Protein A
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Virus
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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