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Invitrogen™ ZNF521 Polyclonal Antibody
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Catalog No. PIPA572984
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100 μL
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PIPA572984 100 μL
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Catalog No. PIPA572984 Supplier Invitrogen™ Supplier No. PA572984
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Description

Rabbit Polyclonal Antibody

ZNF521 Polyclonal Antibody for IHC (P), ICC/IF

The zinc finger protein 521 (ZNF521) is a transcription factor containing an N-terminal transcriptional repressor motif and 30 zinc finger domains. It plays a role in both erythroid cell and osteoblast differentiation during development, inhibiting the activities of early B-cell factor 1 (EBF1) in erythroid cells and Runx2 in osteoblast precursors. ZFP521 binds to both Runx2 and histone deacetylase 3 (HDAC3), promotes their association and antagonizes Runx2 transcriptional activity in a HDAC3-dependent manner, thereby regulating osteoblast differentiation, skeletal development, and bone homeostasis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ZNF521
Applications Immunohistochemistry (Paraffin), Immunocytochemistry
Classification Polyclonal
Concentration 1.11 mg/mL
Conjugate Unconjugated
Formulation PBS with 30% glycerol and 0.05% sodium azide
Gene ZNF521
Gene Accession No. Q6KAS7, Q96K83
Gene Alias B930086A16Rik; early hematopoietic zinc finger protein; Ecotropic viral integration site 3 protein; EHZF; Evi3; LIP3; LYST-interacting protein 3; Zfp521; Zinc finger protein 521; Znf521
Gene Symbols Zfp521, ZNF521
Host Species Rabbit
Immunogen A synthetic peptide made to an internal portion of the human ZNF521 protein (between residues 450-550).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 225207, 25925
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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