ZNF839 Rabbit anti-Human, Polyclonal, Proteintech

Catalog No.	Quantity
50-173-2946	150 μL

Catalog No. 50-173-2946 Supplier Proteintech Group Inc Supplier No. 205391AP150UL

Description

Rabbit Polyclonal Antibody

ZNF839, also known as C14orf131, is an 811 amino acid protein that contains one C2H2-type zinc finger. The gene encoding ZNF839 localizes to chromosome 14 and, due to alternative splicing events, four ZNF839 isoforms are expressed. Chromosome 14 contains about 700 genes and 106 million base pairs and makes up about 3.5% of human cellular DNA. Chromosome 14 encodes the presinilin 1 (PSEN1) gene, which is one of the three key genes associated with the development of Alzheimer′s disease. The SERPINA1 gene is located on chromosome 14 and when defective leads to the genetic disorder alpha1-antitrypsin deficiency. This disorder is characterized by severe lung complications and liver dysfunction. Notably, the immunoglobulin heavy chain locus is found on chromosome 14 and has been identified as a fusion with the chromosome 19 encoded protein BCL3 in the (14; 19) translocations found in a variety of B cell maligcies.

Specifications

• Antigen: ZNF839
• Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Classification: Polyclonal
• Concentration: 0.31 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene: ZNF839
• Gene Accession No.: A8K0R7
• Gene Alias: C14orf131, zinc finger protein 839, ZNF839
• Gene Symbols: ZNF839
• Host Species: Rabbit
• Immunogen: ZNF839 Fusion Protein Ag14573
• Purification Method: Antigen Affinity Chromatography
• Quantity: 150 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 55778
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG