ZNT8 Rabbit anti-Human, Polyclonal, Bioss
Rabbit Polyclonal Antibody
Manufacturer: Bioss BS15382R
DescriptionSlc30A8 is a zinc efflux transporter involved in the accumulation of zinc in intracellular vesicles and is expressed at a high level in the pancreas, particularly in islets of Langerhans, and co-localizes with insulin in the secretory pathway granules of the insulin-secreting INS-1 cells. Allelic variants of Slc30A8 have been identified as major genetic risk factors for the development of Type 2 diabetes, but no genetic association has been found with Type 1 diabetes. Slc30A8 expression in b-cells was found to be influenced by cytokine expression, particularly IFN-gamma and IL-1 beta.
|Immunohistochemistry (Paraffin), Western Blot|
|PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH|
|C820002P14Rik; LOC100347644; SLC30A8; solute carrier family 30 (zinc transporter), member 8; Solute carrier family 30 member 8; wu:fe49g03; Zinc transporter 8; zinc transporter ZnT-8; Znt8; ZnT-8|
|KLH conjugated synthetic peptide derived from human ZNT8.|