ZNT8 Rabbit anti-Human, Polyclonal, Bioss

Rabbit Polyclonal Antibody

Manufacturer:  Bioss BS15382R

Catalog No. 50-198-3719

Description

Slc30A8 is a zinc efflux transporter involved in the accumulation of zinc in intracellular vesicles and is expressed at a high level in the pancreas, particularly in islets of Langerhans, and co-localizes with insulin in the secretory pathway granules of the insulin-secreting INS-1 cells. Allelic variants of Slc30A8 have been identified as major genetic risk factors for the development of Type 2 diabetes, but no genetic association has been found with Type 1 diabetes. Slc30A8 expression in b-cells was found to be influenced by cytokine expression, particularly IFN-gamma and IL-1 beta.

Specifications

• Antigen: ZNT8
• Applications: Immunohistochemistry (Paraffin), Western Blot
• Conjugate: Unconjugated
• Gene: SLC30A8
• Format: Liquid
• Host Species: Rabbit
• Isotype: IgG
• Quantity: 100 μL
• Storage Requirements: -20°C
• Primary or Secondary: Primary
• Gene ID (Entrez): 169026

• Gene Symbol: SLC30A8
• Concentration: 1 μg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
• Gene Accession No.: Q8IWU4
• Gene Alias: C820002P14Rik; LOC100347644; SLC30A8; solute carrier family 30 (zinc transporter), member 8; Solute carrier family 30 member 8; wu:fe49g03; Zinc transporter 8; zinc transporter ZnT-8; Znt8; ZnT-8
• Immunogen: KLH conjugated synthetic peptide derived from human ZNT8.
• Purification Method: Protein A
• Regulatory Status: RUO
• Type: Antibody
• Monoclonal or Polyclonal: Polyclonal
• Target Species: Human