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ZNT8 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501983719
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50-198-3719 100 μL
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Catalog No. 50-198-3719 Supplier Bioss Supplier No. BS15382R
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Description

Rabbit Polyclonal Antibody

Slc30A8 is a zinc efflux transporter involved in the accumulation of zinc in intracellular vesicles and is expressed at a high level in the pancreas, particularly in islets of Langerhans, and co-localizes with insulin in the secretory pathway granules of the insulin-secreting INS-1 cells. Allelic variants of Slc30A8 have been identified as major genetic risk factors for the development of Type 2 diabetes, but no genetic association has been found with Type 1 diabetes. Slc30A8 expression in b-cells was found to be influenced by cytokine expression, particularly IFN-gamma and IL-1 beta.

Specifications

Antigen ZNT8
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene SLC30A8
Gene Accession No. Q8IWU4
Gene Alias C820002P14Rik; LOC100347644; SLC30A8; solute carrier family 30 (zinc transporter), member 8; Solute carrier family 30 member 8; wu:fe49g03; Zinc transporter 8; zinc transporter ZnT-8; Znt8; ZnT-8
Gene Symbols SLC30A8
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human ZNT8.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 169026
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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