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ZNT8 Rabbit anti-Human, Polyclonal, Bioss Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  BiossSupplier Diversity Partner BS15382R

Catalog No. 50-198-3719


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Description

Description

Slc30A8 is a zinc efflux transporter involved in the accumulation of zinc in intracellular vesicles and is expressed at a high level in the pancreas, particularly in islets of Langerhans, and co-localizes with insulin in the secretory pathway granules of the insulin-secreting INS-1 cells. Allelic variants of Slc30A8 have been identified as major genetic risk factors for the development of Type 2 diabetes, but no genetic association has been found with Type 1 diabetes. Slc30A8 expression in b-cells was found to be influenced by cytokine expression, particularly IFN-gamma and IL-1 beta.
Specifications

Specifications

ZNT8
Immunohistochemistry (Paraffin), Western Blot
Unconjugated
SLC30A8
Liquid
Rabbit
IgG
100 μL
-20°C
Primary
169026
SLC30A8
1 μg/mL
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Q8IWU4
C820002P14Rik; LOC100347644; SLC30A8; solute carrier family 30 (zinc transporter), member 8; Solute carrier family 30 member 8; wu:fe49g03; Zinc transporter 8; zinc transporter ZnT-8; Znt8; ZnT-8
KLH conjugated synthetic peptide derived from human ZNT8.
Protein A
RUO
Antibody
Polyclonal
Human
SDS
Documents
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