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Invitrogen™ ZP2 Polyclonal Antibody
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Catalog No. PIPA587653
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100 μL
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PIPA587653 100 μL
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Catalog No. PIPA587653 Supplier Invitrogen™ Supplier No. PA587653
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: KMTVSLPGPI LLLSDDSSFR GVGSSDLKAS GSSGEKSRSE TGEEVGSRGA MDTKGHKTAG DVGSKAVAAV AAFAGVVATL GFIYYLYEKR TVSNH; Positive Samples: SH-SY5Y, HL-60, SW620, Mouse liver, Rat ovary; Cellular Location: Cell membrane, Single-pass type I membrane protein, extracellular matrix, extracellular space.

The zona pellucida is an extracellular matrix that surrounds the oocyte and early embryo. It is composed primarily of three or four glycoproteins with various functions during fertilization and preimplantation development. The protein encoded by this gene is a structural component of the zona pellucida and functions in secondary binding and penetration of acrosome-reacted spermatozoa. The nascent protein contains a N-terminal signal peptide sequence, a conserved ZP domain, a consensus furin cleavage site, and a C-terminal transmembrane domain. It is hypothesized that furin cleavage results in release of the mature protein from the plasma membrane for subsequent incorporation into the zona pellucida matrix. However, the requirement for furin cleavage in this process remains controversial based on mouse studies.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ZP2
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 1.32 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Zp2
Gene Accession No. O54767, P20239, Q05996
Gene Alias 75-kDa rabbit zona pellucida protein; Processed zona pellucida sperm-binding protein 2; zona pellucida 2 glycoprotein; zona pellucida A protein; zona pellucida glycoprotein 2; zona pellucida glycoprotein 2 (sperm receptor); zona pellucida glycoprotein ZP2; zona pellucida glycoprotein ZPA; zona pellucida protein A; Zona pellucida sperm-binding protein 2; ZP2; Zp-2; ZPA
Gene Symbols Zp2
Host Species Rabbit
Immunogen Recombinant protein (or fragment)
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 22787, 7783, 81828
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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