Invitrogen™ ZP4 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA537086

Catalog No. PIPA537086

Description

This antibody detects endogenous protein at a molecular weight of 59 kDa. Purity is >95% by SDS-PAGE.

The mammalian zona pellucida is composed of four major glycoproteins, ZP1, ZP2, ZP3 and ZP4, which may act as sperm receptors. Two forms of porcine ZP4 peptides exist: one consisting of 128 amino acid residues and the other of 133 amino acid residues. These two peptides are identical, except the larger form contains an additional five amino acid sequence at its carboxy-terminal end. Both peptides have two potential N-linked glycosylation sites. The smaller peptide shares 39.1% identity with the amino-terminal region of mouse ZP2 polypeptide. Based on results from animal studies, ZP4 antigen is a promising candidate for the development of a contraceptive vaccine.

Specifications

• Antigen: ZP4
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ZP4
• Gene Alias: Processed zona pellucida sperm-binding protein 4; ZBP; zona pellucida 4; zona pellucida B glycoprotein; zona pellucida glycoprotein 4; Zona pellucida protein B; zona pellucida sperm-binding protein 4; ZP1; ZP4; Zp-4; ZPB
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 282833, 57829
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q12836, Q8CH34
• Gene Symbols: ZP4
• Immunogen: Synthetic peptide corresponding to amino acids 277-322 of human ZP4.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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