ZRANB2 Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Catalog No.	Quantity
50-173-4559	150 μL

Catalog No. 50-173-4559 Supplier Proteintech Group Inc Supplier No. 248161AP150UL

Description

Rabbit Polyclonal Antibody

In WB, a band of ∽48 kDa is detected. The immunogen of this antibody is 1-241aa. No other protein can be recognized by this antibody from the sequence BLAST results.

Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. ZNF265 (Zinc finger protein 265), also known as ZRANB2 (Zinc finger Ran-binding domain-containing protein 2), ZIS, ZIS1 or ZIS2, is a 330 amino acid protein that belongs to the ZRANB2 family. Localized to the nucleus, ZNF265 functions as a splicing factor that is responsible for alternatively splicing Tra-2 beta (transformer-2 beta) transcripts and is thought to interfere with constitutive 5′-splice selection. ZNF265 contains two RanBP2-type zinc fingers through which it conveys its RNA-binding activity. Two isoforms, designated ZIS-1 and ZIS-2, are expressed due to alternative splicing events. Upon DNA damage, ZIS-2 may be phosphorylated by ATM or ATR.

Specifications

• Antigen: ZRANB2
• Applications: Western Blot
• Classification: Polyclonal
• Concentration: 0.2 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene: ZRANB2
• Gene Accession No.: O95218, Q9R020
• Gene Alias: Zinc finger protein 265, Zinc finger, splicing, ZIS, ZIS1, ZIS2, ZNF265, ZRANB2
• Gene Symbols: Zranb2
• Host Species: Rabbit
• Immunogen: ZRANB2 Fusion Protein Ag20487
• Purification Method: Antigen Affinity Chromatography
• Quantity: 150 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 53861, 9406
• Target Species: Human, Mouse
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG