Zyxin Mouse anti-Human, Mouse, Clone: 4D7E7, Proteintech

Catalog No.	Quantity
50-173-6351	150 μL

Catalog No. 50-173-6351 Supplier Proteintech Group Inc Supplier No. 602541IG150UL

Description

Mouse Monoclonal Antibody

Zyxin is involved in focal adhesions, which are actin-rich structures that enable cells to adhere to the extracellular matrix and at which protein complexes involved in signal transduction assemble. Zyxin is a zinc-binding phosphoprotein that concentrates at focal adhesions and along the actin cytoskeleton. Zyxin has an N-terminal proline-rich domain and three LIM domains in its C-terminal half. The proline-rich domain may interact with SH3 domains of proteins involved in signal transduction pathways while the LIM domains are likely involved in protein-protein binding. Zyxin may function as a messenger in the signal transduction pathway that mediates adhesion-stimulated changes in gene expression and may modulate the cytoskeletal organization of actin bundles. Alternative splicing results in multiple transcript variants that encode the same isoform.

Specifications

• Antigen: Zyxin
• Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Classification: Monoclonal
• Clone: 4D7E7
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene: ZYX
• Gene Accession No.: Q15942, Q62523
• Gene Alias: ESP 2, HED 2, ZYX, zyxin, Zyxin 2
• Gene Symbols: ZYX
• Host Species: Mouse
• Immunogen: Zyxin Fusion Protein Ag0419
• Purification Method: Protein G
• Quantity: 150 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 22793, 7791
• Target Species: Human, Mouse
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1